Key historical landmark research malpractice scandals that shocked the international community were the origin of the institution of ethics review prior to carrying out research involving humans. Nonetheless, it is plausible that unethical research is ongoing or may have been conducted in recent times that has escaped public notice, especially in the vulnerable low- and middle-income country contexts. The basic constitution of these committees at some point has not been clearly defined, with most scientists declaring political maneuvers at times. These (...) committees today are characterized by bureaucratic bottlenecks, financial interests, inadequate training in research ethics, and lack of control and coordination of their functions. Compulsory and adequate research ethics training for researchers and ethical committee members could guarantee trust, and appreciation of the utmost importance... (shrink)

Science can reveal or conceal the breathtaking wonders of creation. On one hand, knowledge of the natural world can open us up to greater love for the Creator, give us the means of more neighborly care, and fill us with ever-deepening astonishment. On the other hand, knowledge feeding an insatiable hunger for epistemic mastery can become a means of idolatry, hubris, and damage. Crucial to world-respecting science is the role of wonder: curiosity, perplexity, and astonishment. In this volume, philosopher William (...) Desmond explores the relation of the different modes of wonder to modern science. Responding to his thought are twelve thinkers across the domains of science, theology, philosophy, law, poetry, medicine, sociology, and art restoration. (shrink)

Desmond explores perplexity regarding ultimacy--the metaphysical perplexity that precedes and exceeds scientific and commonsense curiosity.

Treatment informed consent aims to preserve the autonomy of patients in the clinician – patient relationship so as to ensure valid consent. An acceptable method of evaluating understanding of consent information is by assessing the extent of recall by patients of the pieces information believed to have been passed across. When concerns are not satisfactorily addressed from the patients’ perspective, recall of consent information may be low. This study is a questionnaire – based cross – sectional interview of consecutive adult (...) surgical patients who could give their respective medical histories and who were booked for elective major surgical procedures over a period of 7 months in a tertiary health institution in southeastern Nigeria. Four to five days after a formal consent session, during ward admission, extent of recall of information on the nature of the disease condition or diagnosis, the nature of the planned procedure and the risks involved in the planned procedure were assessed and analyzed on the background of how satisfying the consent sessions were from individual patient’s perspective. Generally, the recall of nature of disease condition and nature of planned procedure is better than recall of risks involved in the planned procedure. More specifically however, recall in these 3 domains is significantly better among the patients that affirmed that their concerns were satisfactorily addressed. The findings from this study support that no effort should be spared in ensuring that the consent information are satisfying to the patients from the patients’ viewpoint. (shrink)

Descartes' methodology is ambiguous about the role of empirical evidence in science. This ambiguity does not derive from Rationalist qualms about the specifically empirical character of such evidence; for the apparant clash of experience and reason is explained by the need to re-interpret perceptions in terms of new theories, and by the frequently "contaminated" status of so-called experimental evidence. The ambiguity results, rather, from: (a) Descartes' predilection for "ordinary experience" rather than experiments as a source of warrant, and (b) the (...) looseness of fit between hypotheses and confirming evidence. The mathematical ideal of science is a camouflage for a naive, and conceptually impoverished, empiricism. (shrink)

This book analyses the concept of scientific explanation developed by French disciples of Descartes in the period 1660-1700. Clarke examines the views of authors such as Malebranche and Rohault, as well as those of less well-known authors such as Cordemoy, Gadroys, Poisson and R'egis. These Cartesian natural philosophers developed an understanding of scientific explanation as necessarily hypothetical, and, while they contributed little to new scientific discoveries, they made a lasting contribution to our concept of explanation--generations of scientists in subsequent centuries (...) followed their lead. (shrink)

Articulates the necessity for a comprehensive reconstructive thinking about the meaning of being good.

This is the culmination of a systematic metaphysics written by a world-class philosopher, demonstrating the need for a renewal of metaphysics.

Seeking to renew an ancient companionship between the philosophical andthe religious, this book’s meditative chapters dwell on certain elementalexperiences or happenings that keep the soul alive to the enigma of the divine.William Desmond engages the philosophical work of Pascal, Kant, Hegel,Nietzsche, Shestov, and Soloviev, among others, and pursues with a philosophicalmindfulness what is most intimate in us, yet most universal: sleep, poverty,imagination, courage and witness, reverence, hatred and love, peace and war.Being religious has to do with that intimate universal, (...) beyond arbitrarysubjectivism and reductionist objectivism.In this book, he attempts to look at religion with a fresh and open mind,asking how philosophy might itself stand up to some of the questions posed toit by religion, not just how religion might stand up to the questions posed to it byphilosophy. Desmond tries to pursue a new and different policy, one faithfulto the light of this dialogue. (shrink)

Desmond M. Clarke presents new translations, from French and Latin, of three of the first feminist tracts to support explicitly the equality of men and women: Marie le Jars de Gournay's The Equality of Men and Women, Anna Maria van Schurman's Dissertation, and François Poulain de la Barre's Physical and Moral Discourse concerning the Equality of Both Sexes. These works transformed the language and conceptual framework in which questions about women's equality were subsequently discussed. This edition includes new translations, (...) from French and Latin, of these three feminist authors, excerpts from their related writings, together with an extensive introduction to the religious and philosophical context within which they argued against the traditional view of women's natural inferiority to men. (shrink)

Descartes is possibly the most famous of all writers on the mind, but his theory of mind has been almost universally misunderstood, because his philosophy has not been seen in the context of his scientific work. Desmond Clarke offers a radical and convincing rereading, undoing the received perception of Descartes as the chief defender of mind/body dualism. For Clarke, the key is to interpret his philosophical efforts as an attempt to reconcile his scientific pursuits with the theologically orthodox views (...) of his time. (shrink)

In the past decade, policy-makers in science have been concerned with harmonizing research integrity standards across Europe. These standards are encapsulated in the European Code of Conduct for Research Integrity. Yet, almost every European country today has its own national-level code of conduct for research integrity. In this study we document in detail how national-level codes diverge on almost all aspects concerning research integrity – except for what constitutes egregious misconduct. Besides allowing for potentially unfair responses to joint misconduct by (...) international collaborations, we argue that the divergences raise questions about the envisaged self-regulatory function of the codes of conduct. (shrink)

This book is a defense of speculative philosophy in the wake of Hegel. In a number of wide-ranging, meditative essays, Desmond deals with the criticism of speculative thought in post-Hegelian thinking. He covers the interpretation of Hegelian speculation in terms of the metataxological notion of being and the concept of philosophy that Desmond has developed in two previous works, Philosophy and Its Others, and Desire, Dialectic and Otherness. Though Hegel is Desmond’s primary interlocuter, there are references to (...) Aristophanes, Socrates, Plato, Augustine, Aquinas, Descartes, Kant, Marx, Kierkegaard, Nietzsche, Heidegger, Levinas, and Derrida. Desmond is concerned with the limits of philosophy. The themes of the essays include speculation and historicism, speculation and cult, speculation and representation, evil and dialectic, logos and the comedy of failure. (shrink)

Distrust in scientific experts can be surprisingly stubborn, persisting despite evidence supporting the experts’ views, demonstrations of their competence, or displays of good will. This stubborn distrust is often viewed as a manifestation of irrationality. By contrast, this article proposes a logic of “status distrust”: low-status individuals are objectively vulnerable to collective decision-making, and can justifiably distrust high-status scientific experts if they are not confident that the experts do not have their best interests at heart. In phenomena of status distrust, (...) social status is thus an indicator of distrust, and this has wider implications for the literatures on trust in science and on expert communication. (shrink)

William Desmond sees religion, art, philosophy, and politics as essential and distinctive modes of human practice, manifestations of an intimate universality that illuminates individual and social being. By observing their permeable relations, Desmond captures notes of a clandestine conversation that transforms ontology.

"Rich in new and stimulating ideas, and based on the breadth of reading and depth of knowledge which its wide-ranging subject matter requires, _The Greek Praise of Poverty_ argues impressively and cogently for a relocation of Cynic philosophy into the mainstream of Greek ideas on material prosperity, work, happiness, and power." —_A. Thomas Cole, Professor Emeritus of Classics, Yale University _ "This clear, well-written book offers scholars and students an accessible account of the philosophy of Cynicism, particularly with regard to (...) the Cynics' attachment to a life of poverty and their disdain for wealth. I have truly profited from reading William Desmond’s book." —_Luis Navia, New York Institute of Technology_ William Desmond, taking issue with typical assessments of the ancient Cynics, contends that figures such as Antisthenes and Diogenes were not cultural outcasts or marginal voices in the classical culture of the fifth and fourth centuries B.C. Rather, the Cynic movement had deep and significant roots in what Desmond calls "the Greek praise of poverty." Desmond demonstrates that classical attitudes toward wealth were complex and ambivalent, and allowed for an implicit praise of poverty and the virtues it could inspire. From an economic and political point of view, the poor majority at Athens and elsewhere were natural democrats who distrusted great concentrations of wealth as potentially oligarchical or tyrannical. Hence, the poor could be praised in contemporary literature for their industry, honesty, frugality, and temperance. The rich, on the other hand, were often criticized as idle, unjust, arrogant, and profligate. These perspectives were reinforced by typical Greek experiences of war, and the belief that poverty fostered the virtues of courage and endurance. Finally, from an early date, Greek philosophers associated wisdom with the transcendence of sense experience and of such worldly values as wealth and honor. The Cynics, Desmond asserts, assimilated all of these ideas in creating their distinctive and radical brand of asceticism. Theirs was a startling and paradoxical outlook, but it had broad appeal and would persist to exert a manifold influence in the Hellenistic period and beyond. (shrink)

Far from being pessimistic or nihilistic, as modern uses of the term "cynic" suggest, the ancient Cynics were astonishingly optimistic regarding human nature. They believed that if one simplified one's life—giving up all unnecessary possessions, desires, and ideas—and lived in the moment as much as possible, one could regain one's natural goodness and happiness. It was a life exemplified most famously by the eccentric Diogenes, nicknamed "the Dog," and his followers, called dog-philosophers, _kunikoi, _or Cynics. Rebellious, self-willed, and ornery but (...) also witty and imaginative, these dog-philosophers are some of the most colorful personalities from antiquity. This engaging introduction to Cynicism considers both the fragmentary ancient evidence on the Cynics and the historical interpretations that have shaped the philosophy over the course of eight centuries—from Diogenes himself to Nietzsche and beyond. Approaching Cynicism from a variety of thematic perspectives as well—their critique of convention, praise of natural simplicity, advocacy of self-sufficiency, defiance of Fortune, and freedom—William Desmond offers a fascinating survey of a school of thought that has had a tremendous influence throughout history and is of continuing interest today. _Copub: Acumen Publishing Limited_. (shrink)

Biologists explain organisms’ behavior not only as having been programmed by genes and shaped by natural selection, but also as the result of an organism’s agency: the capacity to react to environmental changes in goal-driven ways. The use of such ‘agential explanations’ reopens old questions about how justified it is to ascribe agency to entities like bacteria or plants that obviously lack rationality and even a nervous system. Is organismic agency genuinely ‘real’ or is it just a useful fiction? In (...) this paper we focus on two questions: whether agential explanations are to be interpreted ontically, and whether they can be reduced to non-agential explanations (thereby dispensing with agency). The Kantian approach we identify interprets agential explanations non-ontically, yet holds agency to be indispensable. Attributing agency to organisms is not to be taken literally in the way we attribute physical properties such as mass or acceleration, but nor is it a mere heuristic or predictive tool. Rather, it is an inevitable consequence of our own rational capacity: as long as we are rational agents ourselves, we cannot avoid seeing agency in organisms. (shrink)

René Descartes is best remembered today for writing 'I think, therefore I am', but his main contribution to the history of ideas was his effort to construct a philosophy that would be sympathetic to the new sciences that emerged in the seventeenth century. To a great extent he was the midwife to the Scientific Revolution and a significant contributor to its key concepts. In four major publications, he fashioned a philosophical system that accommodated the needs of these new sciences and (...) thereby earned the unrelenting hostility of both Catholic and Calvinist theologians, who relied on the scholastic philosophy that Descartes hoped to replace. His contemporaries claimed that his proofs of God's existence in the Meditations were so unsuccessful that he must have been a cryptic atheist and that his discussion of skepticism served merely to fan the flames of libertinism. This is the first biography in English that addresses the full range of Descartes' interest in theology, philosophy and the sciences and that traces his intellectual development through his entire career. (shrink)

0. Introduction: Mereology, Metaphysics, and Speculative Grammar 0.1 Mereology, Ancient and Contemporary 0.11 Mereology is, strictly speaking, the theory of ...

Descartes is possibly the most famous of all writers on the mind, but his theory of mind has been almost universally misunderstood, because his philosophy has not been seen in the context of his scientific work. Desmond Clarke offers a radical and convincing rereading, undoing the received perception of Descartes as the chief defender of mind/body dualism. For Clarke, the key is to interpret his philosophical efforts as an attempt to reconcile his scientific pursuits with the theologically orthodox views (...) of his time. (shrink)

Much has been written on love and friendship, but not a lot on the nature of an enemy, in a manner analogous to the nature of love itself. To understand something about what it means to be an enemy is not at all self-evident. And if we do not know what an enemy is, do we really know what a friend or a lover is? An understanding of what it means to be an enemy might offer us something like the (...) reverse negative of love or friendship. From holding the reversed negative to the light perhaps we can also gain some sight of the "unreversed" original. The article discusses the fact that we live life as something that offers us a certain affirmative delight in the "to be" as good. It explores how this is changed in relation to different forms of threat. It situated the nature of an enemy in terms of the equivocal constitution of the human being as passio essendi and conatus essendi. Different kinds of enemy are investigated by considering the "reversed negatives" of these four forms of love: self-affirming love, erotic love, philia, and agapeic love. (shrink)

A history of the philosopher-king in Greco-Roman antiquity, examining the persistence of Plato's ideas in political philosophy.

Social media has invaded our private, professional, and public lives. While corporations continue to portray social media as a celebration of self-expression and freedom, public opinion, by contrast, seems to have decidedly turned against social media. Yet we continue to use it just the same. What is social media, and how should we live with it? Is it the promise of a happier and more interconnected humanity, or a vehicle for toxic self-promotion? In this essay I examine the very structure (...) of social media communications in order to sketch how we should engage with social media. Social media communications are, I argue, a public communication of private content. This allows connections to be made with others in ways that would not otherwise be possible; however, it also submits the private to a status competition, which in turn is linked to mental health challenges. A ‘virtuous’ engagement with social media means being aware of these dynamics, and choosing to subordinate social media to other, more important goods. (shrink)

Godsends is William Desmond's newest addition to his masterwork on the borderlines between philosophy and theology. For many years, William Desmond has been patiently constructing a philosophical project-replete with its own terminology, idiom, grammar, dialectic, and its metaxological transformation-in an attempt to reopen certain boundaries: between metaphysics and phenomenology, between philosophy of religion and philosophical theology, between the apocalyptic and the speculative, and between religious passion and systematic reasoning. In Godsends, Desmond's newest addition to his ambitious masterwork, (...) he presents an original reflection on what he calls the "companioning" of philosophy and religion. Throughout the book, he follows an itinerary that has something of an Augustinian likeness: from the exterior to the interior, from the inferior to the superior. The stations along the way include: a grappling with the default atheism prevalent in contemporary intellectual culture; an exploration of the middle space, the metaxu between the finite and the infinite; a dwelling with solitudes as thresholds between selving and the sacred; a meditation on idiot wisdom and transcendence in an East-West perspective; an exploration of the different stresses in the mysticisms of Aurobindo and the Arnhem Sermons; dream monologue of autonomy, a suite of Kantian and post-Kantian variations on the story of the prodigal son; a meditation on the beatitudes as exceeding virtue, in light of Aquinas's understanding; culminating in an exploration of Godsends as telling us something significant about the surprise of revelation, in word, idea, and story. Godsends is written for thoughtful persons and scholars perplexed about the place of religion in our time and hopeful for some illuminating companionship from relevant philosophers. It will also interest students of philosophy and religion, especially philosophical theology and philosophical metaphysics. (shrink)

This major new study of Descartes explores a number of key issues, including his use of experience and reason in science; the metaphysical foundations of Cartesian science; the Cartesian concept of explanation and proof; and an empiricist interpretation of the _Regulae_ and the _Discourse_. Dr. Clarke argues that labels such as empiricism and rationalism are useless for understanding Descartes because, at least in his scientific methodology, he is very much an Aristotelian for whom reflection on ordinary experience is the primary (...) source of scientific hypotheses. Descartes traditionally has been presented as a classic example of rationalism in science, especially by philosophers who concentrated their attention on the _Meditations_ or the _Discourse_. A different perspective is gained by reading Descartes as a practicing scientist and by examining his scientific work and correspondence with other seventeenth-century scientists. These texts suggest that the author relies very much on experience, and in some cases on scientific experiments to support his theories or to dispute those of others. Descartes scientific practice is even consistent with a less rationalistic interpretation of the _Regulae_ and the _Discourse_ than is normally defended. (shrink)

Some of the most significant policy responses to cases of fraudulent and questionable conduct by scientists have been to strengthen professionalism among scientists, whether by codes of conduct, integrity boards, or mandatory research integrity training programs. Yet there has been little systematic discussion about what professionalism in scientific research should mean. In this paper I draw on the sociology of the professions and on data comparing codes of conduct in science to those in the professions, in order to examine what (...) precisely the model of professionalism implies for scientific research. I argue that professionalism, more than any other single organizational logic, is appropriate for scientific research, and that codes of conduct for scientists should strengthen statements concerning scientific autonomy and competence, as well as the scientific service ideal. (shrink)

Desmond M. Clarke presents a thematic history of French philosophy from the middle of the sixteenth century to the beginning of Louis XIV's reign. While the traditional philosophy of the schools was taught throughout this period by authors who have faded into permanent obscurity, a whole generation of writers who were not professional philosophers--some of whom never even attended a school or college--addressed issues that were prominent in French public life. Clarke explores such topics as the novel political theory (...) espoused by monarchomachs against Bodin's account of absolute sovereignty; the scepticism of Montaigne, Charron, and Sanches; the ethical discussions of Du Vair, Gassendi, and Pascal; innovations in natural philosophy; theories of the human mind from Jean de Silhon to Cureau de la Chambre and Descartes; and novel arguments in support of women's education and equality. The writers involved were lawyers, political leaders, theologians, and independent scholars who acknowledged the authority of the Bible as a source of knowledge, while raising questions about faith and reason. (shrink)

Codes of ethics currently offer no guidance to scientists acting in capacity of expert. Yet communicating their expertise is one of the most important activities of scientists. Here I argue that expert communication has a specifically ethical dimension, and that experts must face a fundamental trade-off between "actionability" and "transparency" when communicating. Some recommendations for expert communication are suggested.

The dominant view on the ethics of cognitive enhancement (CE) is that CE is beholden to the principle of autonomy. However, this principle does not seem to reflect commonly held ethical judgments about enhancement. Is the principle of autonomy at fault, or should common judgments be adjusted? Here I argue for the first, and show how common judgments can be justified as based on a principle of service.

René Descartes is best remembered today for writing 'I think, therefore I am', but his main contribution to the history of ideas was his effort to construct a philosophy that would be sympathetic to the new sciences that emerged in the seventeenth century. To a great extent he was the midwife to the Scientific Revolution and a significant contributor to its key concepts. In four major publications, he fashioned a philosophical system that accommodated the needs of these new sciences and (...) thereby earned the unrelenting hostility of both Catholic and Calvinist theologians, who relied on the scholastic philosophy that Descartes hoped to replace. His contemporaries claimed that his proofs of God's existence in the Meditations were so unsuccessful that he must have been a cryptic atheist and that his discussion of skepticism served merely to fan the flames of libertinism. This is the first biography in English that addresses the full range of Descartes' interest in theology, philosophy and the sciences and that traces his intellectual development through his entire career. (shrink)

Darwin hypothesized that some animals, when selecting sexual partners, possess a genuine “sense of beauty” that cannot be accounted for by the logic of natural selection. This hypothesis has been notoriously controversial. In this chapter I propose that the concept of agency can be useful to operationalize the “sense of beauty”, and can help identify the conditions under which one can infer that animals are acting as (aesthetic) agents. Focusing on a case study of the behavior of the Pavo cristatus, (...) I identify the types of evidence that would allow for the inference of agency through aesthetic choice. (shrink)